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br Case report We report a case
2019-06-05
Case report We report a case of an 18 year-old Caucasian male who was found to have thrombocytopenia at birth, with a platelet count of 58,000/mm3. Bone marrow biopsy was first performed in 1993, at 13 months of age, and showed 70–80% cellular marrow with occasional megakaryocytes and no evidence
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Almost all the information we have on clinical epidemiology
2019-06-05
Almost all the information we have on clinical epidemiology of patients with interleukin 1 receptor antagonist failure is collected in North America or in western European countriesTherefore, the work of Hisham Dokainish and colleagues in this issue of , is very welcome. Their study provides a clea
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The STAR VT trial is
2019-06-05
The STAR-VT trial is a randomized trial examining the role of ablation in patient with an indication for ICD implantation [97]. The inclusion criteria targeting 562 patients with secondary prevention indications as well as primary prevention patients with inducible VT, where nonischemic cardiomyopat
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Paisey et al recently proposed a simple technique
2019-06-05
Paisey et al. recently proposed a simple technique for recognizing an MI block. In their study, an abrupt change of the CS activation pattern during RF application, under left atrial appendage pacing from a distal-to-proximal to proximal-to-distal direction provided a reliable assessment of MI condu
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It is possible that this
2019-06-05
It is possible that this contradiction may be due to referral bias in the studies of Brugada et al. [20,21]. Second, it is possible that time of day influences the results of PES. The magnitude of ST-segment elevation in the right precordial leads in BS varies spontaneously over days and during the
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Next we evaluated the interatrial and
2019-06-05
Next, we evaluated the interatrial and interatrioventricular synchrony because a long contraction time between the right and left atria was observed during the SSA procedure, dissection of the atrial septum, and patch closure. We were primarily concerned with determining whether the timing of the le
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br Commentary Recordings of the activation sequence from the
2019-06-05
Commentary Recordings of the activation sequence from the CS during tachycardia are expected to help discriminate among atrial tachyarrhythmias [2]. During ongoing typical CCW AFL, most of the CS is activated from proximal to distal, because the CS musculature, by being continuous with the RA myo
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Preclinical studies have shown that adipocytes and MSCs play
2019-06-05
Preclinical studies have shown that adipocytes and MSCs play an important role in migration and dissemination of cancer dnmt [55,56]. Concerning osteosarcoma, one publication has reported that human MSCs injected through the caudal vein of mice bearing Saos-2- induced an increase in tumor volume ass
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br Materials and methods This
2019-06-05
Materials and methods This study included WCD patients with high risk of SCD but did not meet the eligibility criteria for immediate aldehyde dehydrogenase of an implantable cardioverter defibrillator (ICD). Current guidelines endorse indications for WCD therapy [5]. Patients with low left ventr
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Visto el franquismo como el gran
2019-06-01
Visto el franquismo como el gran eje de la discordia, el punto de in flexión se produjo en 1949 con motivo de la presentación en la onu de una propuesta conjunta de cuatro países de América Latina: Brasil, Bolivia, Colombia y Perú. La propuesta de resolución del cuatripartito latinoamericano (proyec
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br Discussion GISTs originate from the
2019-06-01
Discussion GISTs originate from the interstitial smad inhibitor of Cajal. They occur commonly in the stomach (50–60%), the small intestine (30–35%), the colon and rectum (5%) and the esophagus ( from 26 to 87 years (mean, 60.7 years). The tumors originated from the stomach, small bowel, rectum an
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Heat shock facilitates the folding of
2019-06-01
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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br Diarrhoeal diseases are the second most
2019-06-01
Diarrhoeal diseases are the second most common cause of deaths of children, killing more than 1·5 million children annually and infecting billions more. The recently released Global Action Plan for Pneumonia and Diarrhoea (GAPPD) is a comprehensive strategy document outlining plans to end preventa
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Vaccinated individuals might represent a
2019-06-01
Vaccinated individuals might represent a safer source of hyperimmune serum. Two vaccine candidates will be tested soon in west Africa. If serum from vaccinated individuals has neutralising activity against the virus in cell models, this serum could be used as adjuvant therapy for EVD. In parallel, a
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Participants identified the most important values
2019-05-31
Participants identified the most important values that latrunculin a should inform the NHHRA, proposing that research topics focus on vulnerable populations, improve the health system of Papua New Guinea, and contribute to decision-making and policy-making (). After research topics were identified
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