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shows the hormonal and follicular
2022-09-08

shows the hormonal and follicular growth profile of the woman who ovulated in both cycles. In cycle 1, an LH surge occurred on day 17, when serum oestradiol concentration was 210.5 pg/ml and follicle diameter 17 mm. In cycle 2, ganirelix administration was continued until day 19 instead of until th
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To shed more light on the binding of benzophenanthridine to
2022-09-08

To shed more light on the binding of benzophenanthridine to GlyT1, we studied how the replacement of certain residues around the sanguinarine sensitive cysteine 475 previously identified (Jursky et al., 2012) affects GlyT1 inhibition of by these alkaloids. Based on these results we propose a putativ
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angiopoietin The second experiment investigated the possible
2022-09-07

The second experiment investigated the possible neuronal mechanism underlying the effect of acupuncture. The baseline level of methamphetamine consumption in each group was similar, as in the first experiment (Fig. 2A). Acupuncture at HT7 also significantly inhibited the methamphetamine self-adminis
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The normal function of the FBPase enzyme is
2022-09-07

The normal function of the FBPase enzyme is to catalyze the hydrolysis of F1,6BP to F6P. This activity is induced by diabetes and starvation and is increased in diabetic rats. The level of FBPase can be normalized by insulin, however, similar information is not available from diabetic patients. FBPa
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We compared the mixotrophic growth of mutant
2022-09-07

We compared the mixotrophic growth of mutant DRHB1486 and the wild-type at different light intensities. The mutant grew at a similar rate as the wild-type at a low light intensity but much more slowly at a high light intensity (Fig. 3). Because the slr2094 mutant was unable to grow under photoautotr
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Arsenic is generally found in the
2022-09-07

Arsenic is generally found in the form of iAs in arsenic plants. Arsenic is primarily metabolized in the liver through methylation processes. Human metabolism of arsenic results in the formation of the methylarsenic metabolites, MMA and DMA, which are more water soluble (Khaleghian et al., 2014; Wei
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br Acknowledgements The authors have
2022-09-07

Acknowledgements The authors have no ethical conflicts to disclose. The authors have no conflicts of interest to declare. This work was funded by the Research Council of Lithuania. Introduction This paper studies whether there is a causal influence of the risk-taking incentives provided by op
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kh7 br Acknowledgments This research was supported by the Na
2022-09-07

Acknowledgments This research was supported by the National Institutes of Health Grants GM58442 and GM084152, as well as the National Institutes of Health Predoctoral Training Grant 5T32GM008700-13. We thank Eric Oldfield (University of Illinois, Urbana-Champaign) for providing the FDPS inhibitor
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PKC potentiates insulin release in beta cells however
2022-09-07

PKC potentiates insulin release in beta cells; however, it is currently not clear how this is mechanistically accomplished in living ha tag peptide [15]. First, we discuss PKC structure, regulation, and activation in beta cells. Then, we address two fundamental questions: (1) what is the specific ef
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br Application of TIRFM to
2022-09-07

Application of TIRFM to visualizing exocytosis TIRFM was first used to visualize exocytosis from large secretory granules from chromaffin 6XHis (Steyer et al., 1997). Before that, visualization of secretory organelle was strictly limited to a few exceptions, such as mast cell of mutant mice, or s
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br Materials and methods br Results and discussion br
2022-09-07

Materials and methods Results and discussion Conclusion The as-designed system was based on the assembly of MSN-Cy and TPGS, which was dominated by π-π stacking interactions. By the strong mutual force, Cypate and TPGS formed a compact layer around the MSN core, which blocked the drug leaka
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BMP signals play pivotal roles in
2022-09-07

BMP signals play pivotal roles in the various processes of chondrogenesis [12], [13]. At early stages of chondrogenesis, BMP signaling regulates the differentiation of mesenchymal TIC10 into chondrocytes via the induction of Sox9[29]. The loss of Noggin, a BMP antagonist, results in the overgrowth o
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Evidence indicates that astrocytes play a role in the
2022-09-07

Evidence indicates that astrocytes play a role in the modulation of NMDAR activity in the CA1 (Henneberger et al., 2010; Papouin et al., 2017a, Papouin et al., 2017b; Robin et al., 2018). Therefore, we sought to examine whether astrocytes are involved in the H1 receptor antagonist/inverse agonist-in
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Introduction Histamine Imidazolyl ethylamine is an
2022-09-07

Introduction Histamine [2-(4-Imidazolyl)-ethylamine] is an important mediator of many physiological and pathological processes including inflammation, gastric Folinic acid secretion, neuromodulation, regulation of immune function, cell proliferation and differentiation, among others. Histamine exe
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br Conclusions br Acknowledgement br Introduction The macrop
2022-09-06

Conclusions Acknowledgement Introduction The macrophage is an important cell species that plays key roles in innate immune responses and inflammatory reactions through phagocytosis of foreign bodies and secretion of inflammatory mediators such as interleukin (IL)-1, tumor necrosis factor (T
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