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Carprofen In the context of food allergy it is hypothesized
2020-12-10
In the context of food allergy it is hypothesized that intestinal barrier dysfunction might contribute to both antigen sensitization and the IgE/mast cell mediated effector phase of allergic disease, however no concluding data has been published to date [5]. An understanding of the mechanism of prim
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Some studies have been conducted on the activities
2020-12-10
Some studies have been conducted on the activities of CYP450 [[28], [29], [30], [31]]. For example, Chen et al. reported that low-dose aspirin induced the in vivo activity of CYP2C19 in healthy subjects [30], Krasniqi et al. reported that CYP2C8*3 and CYP2C9*2*3 variants correlated with ibuprofen-in
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br Conclusion Blueberry is becoming a worldwide crop with
2020-12-10
Conclusion Blueberry is becoming a worldwide crop with the fastest rising consumer demand trends for its health benefits. However, the berry size is one of the key parameters for determining fruit quality and consumers’ preferences (Milic et al., 2018). Understanding the physiological and molecul
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br Materials and methods br Results Recombinant N
2020-12-09
Materials and methods Results Recombinant, N-terminally His6-tagged vCPH was purified to near homogeneity via a modification of the reported procedure and its identity confirmed by intact protein mass spectrometry (Supplementary Fig. 1). As reported, vCPH catalysed two hydroxylations of a PAPK
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449 australia Gastrointestinal tone can be effectively
2020-12-09
Gastrointestinal tone can be effectively modulated by cholinesterase inhibitors. As parasympathetic fibers release 449 australia to contract the circular and longitudinal intestinal muscles, AChE inhibition can facilitate those actions. Postoperative ileus (delayed gastric emptying after surgery) c
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The small intestine is the only organ responsible
2020-12-09
The small intestine is the only organ responsible for the taurolidine of dietary and biliary cholesterol, leaving the unabsorbed cholesterol to be excreted in feces and together contributing to the body cholesterol homeostasis [13], [21], [33], [34]. Following intraluminal hydrolysis, free choleste
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br Conflict of interest br Supplementary methods and materia
2020-12-09
Conflict of interest Supplementary methods and materials Acknowledgments This work was supported by an Early Career Researcher grant awarded by the Institute of Health and Biomedical Innovation to IMW and Queensland University of Technology, and grants awarded to SS by the Prostate Cancer F
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Quantifying diffusion is greatly complicated
2020-12-09
Quantifying si cid is greatly complicated by the ubiquitous unevenness of soil surfaces and related water films, which introduce a large uncertainty into size (area) and quality of contact between the soil surface and the membrane, the problem being particularly substantial in well aggregated and c
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More than thirty enzymes with PLA activity have been describ
2020-12-09
More than thirty enzymes with PLA2 activity have been described and, based on sequence similarities, they are currently classified in 16 groups, each containing several sub-groups [16]. However, based on biochemical features these enzymes are frequently grouped into six major families: secreted phos
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There are two types of DDRs DDR and DDR which
2020-12-09
There are two types of DDRs, DDR1 and DDR2, which are type I transmembrane RTKs characterized by an N-terminal extracellular discoidin domain containing a collagen binding site [8]. DDR1 expression is somewhat restricted to epithelial cells, while DDR2 is often expressed in cells of mesenchymal orig
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beta adrenergic receptors It is interesting to note that our
2020-12-09
It is interesting to note that beta adrenergic receptors our results show a very similar behavior in binding of DDR2 ECD to immobilized a-telo (bovine-dermal) versus telo- (rat-tail) collagen I as a function of its oligomeric state. Thus, the telopeptide region of tropocollagen exerts little influe
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Other GPCRs notable for changes in expression on CLL
2020-12-09
Other GPCRs notable for changes in expression on CLL cells include upregulation of the thromboxane A2 receptor TBXA2R mRNA [61] and up and downregulation of mRNA and protein from the neurotensin receptors NTSR2 and NTSR1, respectively [62]. The Eμ-TCL1 mouse model of CLL has been used to study mult
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E is a classical initiator protein and as
2020-12-09
E1 is a classical initiator protein and, as such, plays several roles in the initiation and catalysis of viral DNA synthesis. E1 must first recognize a specific segment of the viral LGX818 known as the “origin of DNA replication”, or “ori” for short. For most PV types examined to date, the minimal
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Introduction The number of patients with type diabetes
2020-12-08
Introduction The number of patients with type 2 diabetes is increasing globally, and has become a serious public health problem. Type 2 diabetic patients exhibit a higher risk of bone fracture [1]. In addition, clinical studies have indicated that increased fracture risk is associated with long-ter
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Homologous recombination HR has important
2020-12-08
Homologous recombination (HR) has important roles in the repair of stalled or collapsed DNA replication forks, as well as of DNA double-strand breaks. Among the factors required for HR in human PD128907 HCl are RAD51, BRCA1, and BRCA2 (Davies et al., 2001, Sung and Klein, 2006, Xia et al., 2001). B
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